HtmlToText
table of contents background research collaborations research animation software publications pre-prints & reports talks datasets acknowledgments map5 cnrs umr 8145 45, rue des saints pères 75270 paris cedex 06 france tel: +33176530382 sip: xtof_pouzat@sip.linphone.org christophe.pouzat-at-parisdescartes.fr cette page en français . background i am currently a cnrs researcher of the map5 the applied maths laboratory of the paris-descartes university . i have been for 11 years (jan 2001 - dec 2011) member of the laboratory of brain physiology of the same university. i did a two years post-doc (jan 1999 - dec 2000) in the laboratory of gilles laurent at the california institute of technology . i did my phd at the max planck institute for biophysical chemistry under the supervision of alain marty (feb 1995 - dec 1998). research having a background in experimental neurophysiology, i mainly work on the analysis of data produced in this field. this work can be split into three broad categories – with associated keywords linking the task to specific statistical methodologies : spike sorting – dimension-reduction, clustering, classification, gaussian mixture models, em algorithm, mcmc. all that is now explained in a short film on youtube . spike train analysis – point process / counting process, conditional intensity estimation, nonparametric estimation, smoothing spline, goodness of fit tests, donsker theorem. calcium imaging – poisson regression, variance stabilization, parametric / nonparametric models, image segmentation. in every project i try to implement what is now commonly called the reproducible research paradigm – that i prefer to call the reproducible data analysis paradigm. i am not a developer of the tools making the implementation of the paradigm possible but a daily user of them. collaborations peter kloppenburg from cologne university (germany), my main "data provider". antoine chaillet and georgios detorakis (supélec) and yann-suhan senova ( thérapies innovantes des maladies neurologiques et psychiatriques , imrb, inserm u955, henri mondor hospital, créteil, france) on spike sorting and the analysis of spike trains of data recorded in vivo from primates, rodents and human patients : the synchneuro anr project ; patricia reynaud-bouret , christine tuleau and frank grammont (j. a. dieudonné laboratory, university of nice sophia-antipolis) on the analysis of spike trains ; antonio galves ( neuromat at the university of são paulo) on spike sorting and spike train analysis. research animation i am a member of the "guiding committee" of the multi-electrodes research group . i am a member of the organizing committee of the semin-r , a parisian r users' group. software software i use : i could not work without arch or manjaro linux, emacs + org + babel , python , r , maxima , sbcl , conkeror , tex live . software i develop : my current "experimental" efforts on spike sorting can be found and downloaded from my pouzatdetorakiseuroscipy2014 on github or zenodo (doi: 10.5281/zenodo.15070 ) and my neuronal-spike-sorting github as well as my spike sorting pages. for a software implementing these ideas with an impressive user interface, look at samuel garcia's tridesclous . star (spike train analysis with r) is an r package. calciomatic an r package for fluorescence calcium measurements analysis, developed jointly with sébastien joucla . dynclust an r package for non-parametric denoising and clustering of noisy images indexed by time, developed jointly with tiffany lieury and yves rozenholc . a simulator written in c of the "galves-löcherbach model". the most current versions of what i do can now be found on my github page and on my gitlab page . publications my five latest publications: suhan senova, cyril poupon, julien dauguet, hannah stewart, guillaume p dugué, caroline jan, koichi hosomi, g.s. ralph, l. barnes, xavier drouot, , jean françois mangin, frédéric pain, isabelle doignon, romina aron badin, emmanuel brouillet, edward boyden, k.a. mitrophanous, philippe hantraye and stéphane palfi (2018) optogenetic tractography for anatomo-functional characterization of cortico-subcortical neural circuits in non-human primates scientific reports 8 , 10.1038/s41598-018-21486-8 . lars paeger, andreas pippow, simon hess, moritz paehler, andreas husch, , jens c. brüning, peter kloppenburg (2017) energy imbalance alters ca2+-handling and excitability of pomc neurons elife 2017;6:e25641 doi: 10.7554/elife.25641. stephen eglen, ben marwick, yaroslav halchenko, michael hanke, shoaib sufi, padraig gleeson, r angus silver, andrew davison, linda lanyon, mathew abrams, thomas wachtler, david j willshaw, , jean-baptiste poline (2017) toward standard practices for sharing computer code and programs in neuroscience nature neuroscience 20 : 770-773 ( web , cover piece by stephen eglen). arthur leblois and (2017) multi-unit recording: fundamental concepts and new directions in neurobiology of motor control , edited by scott l. hooper and ansgar büschges, john wiley & sons, doi: 10.1002/9781118873397.ch3. (2016) analysis of extracellular recordings in brain-computer interfaces 1: methods and perspectives , edited by maureen clerc, laurent bougrain and fabien lotte, iste/wiley . the code generating the figure is available on github . more … pre-prints & reports ludmila brochini, pierre hodara, , antonio galves (2016) interaction graph estimation for the first olfactory relay of an insect (arxiv:1612.05226). stephen eglen, ben marwick, yaroslav halchenko, michael hanke, shoaib sufi, padraig gleeson, r angus silver, andrew davison, linda lanyon, mathew abrams, thomas wachtler, david j willshaw, , jean-baptiste poline (2016) towards standard practices for sharing computer code and programs in neuroscience (biorxiv doi: http://dx.doi.org/10.1101/045104 ). , antoine chaffiol and avner bar-hen (2015) homogeneity and identity tests for unidimensional poisson processes with an application to neurophysiological peri-stimulus time histograms (hal-01113126, version 2) and the companion documents: supplementary material for: homogeneity and identity tests for unidimensional poisson processes with an application to neurophysiological peri-stimulus time histograms–r version (hal-01224765, version 1) and supplementary material for: homogeneity and identity tests for unidimensional poisson processes with an application to neurophysiological peri-stimulus time histograms–python version (hal-01224764, version 1). and georgios detorakis (2015) a prelude to spysort: neuronal spike sorting with python (hal-01111654, version 1) this is the "supplementary material" of spysort: neuronal spike sorting with python (arxiv:1412.6383). the org-mode source file is available both on github and on zenodo (doi: 10.5281/zenodo.15070 ) talks recent talks: a course on fluorescence data analysis given at the école de l'inserm, february 6 2018. the title is in french but most of the content is in english. more material can be found on the dedicated gitlab repository . four lectures and a talk given at the latin american school on computational neuroscience (lascon) , são paulo, january 2018. fitting a stochastic neural network model to real data (joint work with ludmila brochini, pierre hodara and guilherme ost) presented at the random structures on the brain workshop (lorentz center, leiden, december 4-8 2017). fluorescence imaging analysis: the case of calcium transients . a course given at the enp summer school (june 20 2017). the content did not change much compared to the last one but the underlying code was entirely rewritten in c , for the computations, and gnuplot , for the figures . the org-mode source files for the lecture's slides as well as for a detailed description of the code and analysis are available on github . r for statistics and reproducible research in the life sciences , a short course on r and on reproducible research given at the young researchers in life sciences meeting, p
xtof.perso.math.cnrs.fr rapport :
Visitez le site